Chemotherapeutic targets in parasites : contemporary strategies / Tag E. Mansour ; with the assistance of Joan MacKinnon Mansour.
Mansour, Tag E.Call Number | 616.9/6061 |
Author | Mansour, Tag E., author. |
Title | Chemotherapeutic targets in parasites : contemporary strategies / Tag E. Mansour ; with the assistance of Joan MacKinnon Mansour. |
Physical Description | 1 online resource (xiv, 226 pages) : digital, PDF file(s). |
Notes | Title from publisher's bibliographic system (viewed on 05 Oct 2015). |
Summary | Parasitic infections are the most prevalent of human diseases, and researchers continue to face the challenge of designing drugs to successfully counteract them. Chemotherapeutic Targets in Parasites analyzes the critical metabolic reactions and structural features essential for parasite survival, and advocates the latest molecular strategies with which to identify effective antiparasitic agents. An introduction to the early development of parasite chemotherapy is followed by an overview of biophysical techniques and genomic and proteomic analysis. Several chapters are devoted to specific types of chemotherapeutic agents and their targets in malaria, trypanosomes, leishmania and amitochondrial protists. Chapters on helminths include metabolic, neuromuscular, microtubular and tegumental targets. Emphasized throughout is the design of more selective and less toxic drugs than in the past. This book will be especially relevant to medical and clinical researchers and to graduate students in parasitology, pharmacology, medicine, microbiology, and biochemistry. |
Added Author | Mansour, Joan MacKinnon, author. |
Subject | Antiparasitic agents. Parasitic diseases Chemotherapy. |
Multimedia |
Total Ratings:
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Summary | Parasitic infections are the most prevalent of human diseases, and researchers continue to face the challenge of designing drugs to successfully counteract them. Chemotherapeutic Targets in Parasites analyzes the critical metabolic reactions and structural features essential for parasite survival, and advocates the latest molecular strategies with which to identify effective antiparasitic agents. An introduction to the early development of parasite chemotherapy is followed by an overview of biophysical techniques and genomic and proteomic analysis. Several chapters are devoted to specific types of chemotherapeutic agents and their targets in malaria, trypanosomes, leishmania and amitochondrial protists. Chapters on helminths include metabolic, neuromuscular, microtubular and tegumental targets. Emphasized throughout is the design of more selective and less toxic drugs than in the past. This book will be especially relevant to medical and clinical researchers and to graduate students in parasitology, pharmacology, medicine, microbiology, and biochemistry. |
Notes | Title from publisher's bibliographic system (viewed on 05 Oct 2015). |
Subject | Antiparasitic agents. Parasitic diseases Chemotherapy. |
Multimedia |