Bacterial protein toxins : role in the interference with cell-growth regulation / edited by Alistair J. Lax.
| Call Number | 571.8/4 |
| Title | Bacterial protein toxins : role in the interference with cell-growth regulation / edited by Alistair J. Lax. |
| Physical Description | 1 online resource (xiv, 239 pages) : digital, PDF file(s). |
| Series | Advances in molecular and cellular microbiology ; 7 |
| Notes | Title from publisher's bibliographic system (viewed on 05 Oct 2015). |
| Contents | Toxins and the interaction between bacterium and host / Alistair J. Lax -- The mitogenic Pasteurella multocida toxin and cellular signalling / Gillian D. Pullinger -- Rho-activating toxins and growth regulation / Gudula Schmidt and Klaus Aktories -- Cytolethal distending toxins : a paradigm for bacterial cyclostatins / Bernard Ducommun and Jean De Rycke -- Bartonella signalling and endothelial cell proliferation / Garret Ihler, Anita Verma, and Javier Arevalo -- Type III-delivered toxins that target signalling pathways / Luís J. Mota and Guy R. Cornelis -- Bacterial toxins and bone remodelling / Neil W.A. McGowan [and others] -- Helicobacter pylori mechanisms for inducing epithelial cell proliferation / Michael Naumann and Jean E. Crabtree -- Bacteria and cancer / Christine P.J. Caygill and Michael J. Hill -- What is there still to learn about bacterial toxins? / Alistair J. Lax. |
| Summary | Bacterial toxins that act inside cells interact very specifically with key components of the cell and some even manipulate the cell in subtle ways for their own purposes. These potent toxins, described in this 2005 book, will be of interest to both microbiologists and cell biologists. Some of these toxins are conventional multidomain toxins that are self-programmed to enter cells. Others are delivered by type III mechanisms, often as a package of potent molecules. The molecular targets for all these toxins mediate signal transduction and the cell cycle to regulate the crucial processes of cell growth, cell division and differentiation. Thus these potent toxins are not only responsible for disease, but also provide a powerful set of tools with which to interrogate the biology of the cell. In addition such toxins may act directly to promote carcinogenesis and hence their study is also of interest in a wider context. |
| Added Author | Lax, Alistair J., 1953- editor. |
| Subject | Bacterial Toxins. |
| Multimedia |
Total Ratings:
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$a Bacterial toxins that act inside cells interact very specifically with key components of the cell and some even manipulate the cell in subtle ways for their own purposes. These potent toxins, described in this 2005 book, will be of interest to both microbiologists and cell biologists. Some of these toxins are conventional multidomain toxins that are self-programmed to enter cells. Others are delivered by type III mechanisms, often as a package of potent molecules. The molecular targets for all these toxins mediate signal transduction and the cell cycle to regulate the crucial processes of cell growth, cell division and differentiation. Thus these potent toxins are not only responsible for disease, but also provide a powerful set of tools with which to interrogate the biology of the cell. In addition such toxins may act directly to promote carcinogenesis and hence their study is also of interest in a wider context.
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| Summary | Bacterial toxins that act inside cells interact very specifically with key components of the cell and some even manipulate the cell in subtle ways for their own purposes. These potent toxins, described in this 2005 book, will be of interest to both microbiologists and cell biologists. Some of these toxins are conventional multidomain toxins that are self-programmed to enter cells. Others are delivered by type III mechanisms, often as a package of potent molecules. The molecular targets for all these toxins mediate signal transduction and the cell cycle to regulate the crucial processes of cell growth, cell division and differentiation. Thus these potent toxins are not only responsible for disease, but also provide a powerful set of tools with which to interrogate the biology of the cell. In addition such toxins may act directly to promote carcinogenesis and hence their study is also of interest in a wider context. |
| Notes | Title from publisher's bibliographic system (viewed on 05 Oct 2015). |
| Contents | Toxins and the interaction between bacterium and host / Alistair J. Lax -- The mitogenic Pasteurella multocida toxin and cellular signalling / Gillian D. Pullinger -- Rho-activating toxins and growth regulation / Gudula Schmidt and Klaus Aktories -- Cytolethal distending toxins : a paradigm for bacterial cyclostatins / Bernard Ducommun and Jean De Rycke -- Bartonella signalling and endothelial cell proliferation / Garret Ihler, Anita Verma, and Javier Arevalo -- Type III-delivered toxins that target signalling pathways / Luís J. Mota and Guy R. Cornelis -- Bacterial toxins and bone remodelling / Neil W.A. McGowan [and others] -- Helicobacter pylori mechanisms for inducing epithelial cell proliferation / Michael Naumann and Jean E. Crabtree -- Bacteria and cancer / Christine P.J. Caygill and Michael J. Hill -- What is there still to learn about bacterial toxins? / Alistair J. Lax. |
| Subject | Bacterial Toxins. |
| Multimedia |