Systems genetics : linking genotypes and phenotypes / edited by Florian Markowetz, Cancer Research UK, Cambridge Research Institute, Michael Boutros, German Cancer Research Center, Heidelberg.
| Call Number | 576.5 |
| Title | Systems genetics : linking genotypes and phenotypes / edited by Florian Markowetz, Cancer Research UK, Cambridge Research Institute, Michael Boutros, German Cancer Research Center, Heidelberg. |
| Physical Description | 1 online resource (xi, 258 pages) : digital, PDF file(s). |
| Series | Cambridge series in systems genetics |
| Notes | Title from publisher's bibliographic system (viewed on 05 Oct 2015). |
| Summary | Whereas genetic studies have traditionally focused on explaining heritance of single traits and their phenotypes, recent technological advances have made it possible to comprehensively dissect the genetic architecture of complex traits and quantify how genes interact to shape phenotypes. This exciting new area has been termed systems genetics and is born out of a synthesis of multiple fields, integrating a range of approaches and exploiting our increased ability to obtain quantitative and detailed measurements on a broad spectrum of phenotypes. Gathering the contributions of leading scientists, both computational and experimental, this book shows how experimental perturbations can help us to understand the link between genotype and phenotype. A snapshot of current research activity and state-of-the-art approaches to systems genetics are provided, including work from model organisms such as Saccharomyces cerevisiae and Drosophila melanogaster, as well as from human studies. |
| Added Author | Markowetz, Florian, editor. Boutros, Michael, editor. |
| Subject | Phenotype. GENETICS. Functional genomics. |
| Multimedia |
Total Ratings:
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| Summary | Whereas genetic studies have traditionally focused on explaining heritance of single traits and their phenotypes, recent technological advances have made it possible to comprehensively dissect the genetic architecture of complex traits and quantify how genes interact to shape phenotypes. This exciting new area has been termed systems genetics and is born out of a synthesis of multiple fields, integrating a range of approaches and exploiting our increased ability to obtain quantitative and detailed measurements on a broad spectrum of phenotypes. Gathering the contributions of leading scientists, both computational and experimental, this book shows how experimental perturbations can help us to understand the link between genotype and phenotype. A snapshot of current research activity and state-of-the-art approaches to systems genetics are provided, including work from model organisms such as Saccharomyces cerevisiae and Drosophila melanogaster, as well as from human studies. |
| Notes | Title from publisher's bibliographic system (viewed on 05 Oct 2015). |
| Subject | Phenotype. GENETICS. Functional genomics. |
| Multimedia |