Continuous biopharmaceutical processes : chromatography, bioconjugation, and protein stability / David Pfister, Lucrèce Nicoud, Massimo Morbidelli.

Pfister, David, 1988-
Call Number
615.7
Author
Pfister, David, 1988- author.
Title
Continuous biopharmaceutical processes : chromatography, bioconjugation, and protein stability / David Pfister, Lucrèce Nicoud, Massimo Morbidelli.
Physical Description
1 online resource (xix, 327 pages) : digital, PDF file(s).
Series
Cambridge series in chemical engineering
Notes
Title from publisher's bibliographic system (viewed on 24 Sep 2018).
Contents
Introduction to biopharmaceutical processes -- Fundamentals of protein chromatography -- Counter-current separation processes -- Counter-current chromatography for the capture step -- Counter-current chromatography for the polishing steps -- Protein conjugation -- Protein aggregation in biopharmaceutical processes.
Summary
This innovative reference provides a coherent and critical view on the potential benefits of a transition from batch to continuous processes in the biopharmaceutical industry, with the main focus on chromatography. It also covers the key topics of protein stability and protein conjugation, addressing the chemical reaction and purification aspects together with their integration. This book offers a fine balance between theoretical modelling and illustrative case studies, between fundamental concepts and applied examples from the academic and industrial literature. Scientists interested in the design of biopharmaceutical processes will find useful practical methodologies, in particular for single-column and multi-column chromatographic processes.
Added Author
Nicoud, Lucrèce, 1988- author
Morbidelli, Massimo, author.
Subject
Protein drugs.
Pharmaceutical technology.
Multimedia
Total Ratings: 0
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No Reviews to Display
Summary
This innovative reference provides a coherent and critical view on the potential benefits of a transition from batch to continuous processes in the biopharmaceutical industry, with the main focus on chromatography. It also covers the key topics of protein stability and protein conjugation, addressing the chemical reaction and purification aspects together with their integration. This book offers a fine balance between theoretical modelling and illustrative case studies, between fundamental concepts and applied examples from the academic and industrial literature. Scientists interested in the design of biopharmaceutical processes will find useful practical methodologies, in particular for single-column and multi-column chromatographic processes.
Notes
Title from publisher's bibliographic system (viewed on 24 Sep 2018).
Contents
Introduction to biopharmaceutical processes -- Fundamentals of protein chromatography -- Counter-current separation processes -- Counter-current chromatography for the capture step -- Counter-current chromatography for the polishing steps -- Protein conjugation -- Protein aggregation in biopharmaceutical processes.
Subject
Protein drugs.
Pharmaceutical technology.
Multimedia