Left-Right Asymmetry in Vertebrate Development [electronic resource] / by Maria L. López-Gracia, Marian Ros.

Call Number	612
Author	López-Gracia, Maria L. author.
Title	Left-Right Asymmetry in Vertebrate Development by Maria L. López-Gracia, Marian Ros.
Physical Description	XII, 126 p. 16 illus., 13 illus. in color. online resource.
Series	Advances in Anatomy Embryology and Cell Biology, 0301-5556 ; 188
Contents	Establishment of Left-Right Asymmetry -- Signaling Pathways with a Predominant Role in Left-Right Patterning -- Mouse Models of Laterality -- Genetics of Human Alterations of Organ Situs -- Concluding Remarks.
Summary	Externally the vertebrate body plan presents a bilateral symmetry in relation to the midline. However, inside the body the distribution of the visceral organs follows a very particular pattern that is not symmetrical in relation to the midline. The last 10 years have seen remarkable advances in our understanding of how the internal asymmetries typical of the vertebrate body are established and controlled. The use of different development models has permitted to uncover fascinating ways of creating asymmetry, like the activity of the nodal cilia. A host of studies has also unravelled the involvement of many genes in the left right patterning pathway. Based on this knowledge the genetic basis of human laterality defects are beginning to be revealed. It is a major challenge now to understand how all these genes control left right development as well as the complex set of interactions established between them.
Added Author	Ros, Marian. author. SpringerLink (Online service)
Subject	MEDICINE. HUMAN PHYSIOLOGY. Biomedicine. Human Physiology.
Multimedia	http://dx.doi.org/10.1007/978-3-540-36348-4

Libraries with this item

950	Biomedical and Life Sciences (Springer-11642)

Total Ratings: 0

Copies
MARC Record
Reviews
Details


No records found to display.

02753nam a22004695i 4500

001

vtls001568948

003

VRT

005

20170831185700.0

007

cr nn 008mamaa

008

170831s2007 gw | s |||| 0|eng d

020

$a 9783540363484 $9 978-3-540-36348-4

024

$a 10.1007/978-3-540-36348-4 $2 doi

035

$a (DE-He213)978-3-540-36348-4

039

$y 201708311857 $z santha

050

$a QP34-38

072

$a MFG $2 bicssc

072

$a MED075000 $2 bisacsh

082

$a 612 $2 23

100

$a López-Gracia, Maria L. $e author.

245

$a Left-Right Asymmetry in Vertebrate Development $h [electronic resource] / $c by Maria L. López-Gracia, Marian Ros.

264

$a Berlin, Heidelberg : $b Springer Berlin Heidelberg, $c 2007.

300

$a XII, 126 p. 16 illus., 13 illus. in color. $b online resource.

336

$a text $b txt $2 rdacontent

337

$a computer $b c $2 rdamedia

338

$a online resource $b cr $2 rdacarrier

347

$a text file $b PDF $2 rda

490

$a Advances in Anatomy Embryology and Cell Biology, $x 0301-5556 ; $v 188

505

$a Establishment of Left-Right Asymmetry -- Signaling Pathways with a Predominant Role in Left-Right Patterning -- Mouse Models of Laterality -- Genetics of Human Alterations of Organ Situs -- Concluding Remarks.

520

$a Externally the vertebrate body plan presents a bilateral symmetry in relation to the midline. However, inside the body the distribution of the visceral organs follows a very particular pattern that is not symmetrical in relation to the midline. The last 10 years have seen remarkable advances in our understanding of how the internal asymmetries typical of the vertebrate body are established and controlled. The use of different development models has permitted to uncover fascinating ways of creating asymmetry, like the activity of the nodal cilia. A host of studies has also unravelled the involvement of many genes in the left right patterning pathway. Based on this knowledge the genetic basis of human laterality defects are beginning to be revealed. It is a major challenge now to understand how all these genes control left right development as well as the complex set of interactions established between them.

650

$a MEDICINE.

650

$a HUMAN PHYSIOLOGY.

650

$a Biomedicine.

650

$a Human Physiology.

700

$a Ros, Marian. $e author.

710

$a SpringerLink (Online service)

773

$t Springer eBooks

776

$i Printed edition: $z 9783540363477

830

$a Advances in Anatomy Embryology and Cell Biology, $x 0301-5556 ; $v 188

856

$u http://dx.doi.org/10.1007/978-3-540-36348-4

912

$a ZDB-2-SBL

950

$a Biomedical and Life Sciences (Springer-11642)

999

$a VIRTUA

No Reviews to Display

Summary	Externally the vertebrate body plan presents a bilateral symmetry in relation to the midline. However, inside the body the distribution of the visceral organs follows a very particular pattern that is not symmetrical in relation to the midline. The last 10 years have seen remarkable advances in our understanding of how the internal asymmetries typical of the vertebrate body are established and controlled. The use of different development models has permitted to uncover fascinating ways of creating asymmetry, like the activity of the nodal cilia. A host of studies has also unravelled the involvement of many genes in the left right patterning pathway. Based on this knowledge the genetic basis of human laterality defects are beginning to be revealed. It is a major challenge now to understand how all these genes control left right development as well as the complex set of interactions established between them.
Contents	Establishment of Left-Right Asymmetry -- Signaling Pathways with a Predominant Role in Left-Right Patterning -- Mouse Models of Laterality -- Genetics of Human Alterations of Organ Situs -- Concluding Remarks.
Subject	MEDICINE. HUMAN PHYSIOLOGY. Biomedicine. Human Physiology.
Multimedia	http://dx.doi.org/10.1007/978-3-540-36348-4