Default Theme

Conjugation and Deconjugation of Ubiquitin Family Modifiers [electronic resource] : Subcellular Biochemistry / edited by Marcus Groettrup.

Call Number	572.6
Title	Conjugation and Deconjugation of Ubiquitin Family Modifiers Subcellular Biochemistry / edited by Marcus Groettrup.
Physical Description	XX, 252 p. 58 illus., 16 illus. in color. online resource.
Series	Subcellular Biochemistry, 0306-0225 ; 54
Contents	Activation of Ubiquitin and Ubiquitin-Like Proteins -- Control of Ubiquitin Conjugation by Cdc48 and Its Cofactors -- Regulation of Ubiquitin Receptors by Coupled Monoubiquitination -- Control of Cullin-Ring Ubiquitin Ligase Activity by Nedd8 -- Control of Deneddylation by the COP9 Signalosome -- Mechanism, Specificity and Structure of the Deubiquitinases -- Ubiquitin Conjugation and Deconjugation in NF-?B Signaling -- Functions of Linear Ubiquitin Chains in the NF-?B Pathway -- Assembly of K11-Linked Ubiquitin Chains by the Anaphase-Promoting Complex -- Ubiquitin Family Members in the Regulation of the Tumor Suppressor p53 -- Ubiquitylation in the ERAD Pathway -- Pupylation -- Sumo Control -- The In Vivo Functions of Desumoylating Enzymes -- Regulatory Functions of Ubiquitin and SUMO in DNA Repair Pathways -- Sumoylation as a Signal for Polyubiquitylation and Proteasomal Degradation -- In Vivo Functions of Isgylation -- Identification and Validation of ISG15 Target Proteins -- FAT10.
Summary	† 1 a a 4 † 17 10 15 ubiquitin; and of 16 VCP 17 18 20 33 34 34 36 p domain. 41 42 42 43 P U 42 47 binding. C. elegans 16 In 21 22 50 51 52 53 13 and UFD 4 10 of Cdc48. 18 30 of Ufd2. COFACTORS 47 23 13 47 47 47 72 15 15 and of Spt23 p90. Ufd2 and Cdc48. In C. elegans 74 16 75 75 76 76 Ufd2 25 54 54 7 56 p47 7 7 80 30 30 81 82 82 but and CD3 26 DUB COFACTORS 30 UFD3 OTU1 4 Cdc48 30 4 OLE1. 15 27 87 REFERENCES 30 REGULATION OF UBIQUITIN MONOUBIQUITINATION UBIQUITINATION 1 32 7 S) d 33 12 13 14 15 18 19 15 20 21 35 15 15 27 15 31 32 31 33 36 monoubiquitination of pol pol 34 37 34 monoubiquitination. 20 35 trans 3 15 REFERENCES by monoubiquitination. Mol Cell; 2009. UBIQUITIN LIGASE ACTIVITY BY Nedd 1 2 of 41 5 6 8 fold. 9 13 14 edd 43 18 18 K M and k 18 22 23 K M 24 25 K M 26 edd 45 18 27 K M K D 18 25 . 8 10 M 21 28 MECHANISM AND REGULATION OF CRLs 34 41 34 edd 47 48 S. pombe 49 51 p27 and I by SCF and SCF 57 58 59 60 CTD CTD CTD CTD in Cul5 CTD CTD CTD 60 18.
Added Author	Groettrup, Marcus. editor. SpringerLink (Online service)
Subject	LIFE SCIENCES. HUMAN PHYSIOLOGY. MOLECULAR BIOLOGY. PROTEINS. Life Sciences. Protein Science. Human Physiology. Molecular Medicine.
Multimedia	http://dx.doi.org/10.1007/978-1-4419-6676-6

Libraries with this item

950	Biomedical and Life Sciences (Springer-11642)

Total Ratings: 0

Copies
MARC Record
Reviews
Details


No records found to display.

03668nam a22005055i 4500

001

vtls001568473

003

VRT

005

20170831183500.0

007

cr nn 008mamaa

008

170831s2010 xxu| s |||| 0|eng d

020

$a 9781441966766 $9 978-1-4419-6676-6

024

$a 10.1007/978-1-4419-6676-6 $2 doi

035

$a (DE-He213)978-1-4419-6676-6

039

$y 201708311835 $z santha

050

$a QD431-431.7

072

$a PSBC $2 bicssc

072

$a SCI007000 $2 bisacsh

082

$a 572.6 $2 23

245

$a Conjugation and Deconjugation of Ubiquitin Family Modifiers $h [electronic resource] : $b Subcellular Biochemistry / $c edited by Marcus Groettrup.

264

$a New York, NY : $b Springer New York, $c 2010.

300

$a XX, 252 p. 58 illus., 16 illus. in color. $b online resource.

336

$a text $b txt $2 rdacontent

337

$a computer $b c $2 rdamedia

338

$a online resource $b cr $2 rdacarrier

347

$a text file $b PDF $2 rda

490

$a Subcellular Biochemistry, $x 0306-0225 ; $v 54

505

$a Activation of Ubiquitin and Ubiquitin-Like Proteins -- Control of Ubiquitin Conjugation by Cdc48 and Its Cofactors -- Regulation of Ubiquitin Receptors by Coupled Monoubiquitination -- Control of Cullin-Ring Ubiquitin Ligase Activity by Nedd8 -- Control of Deneddylation by the COP9 Signalosome -- Mechanism, Specificity and Structure of the Deubiquitinases -- Ubiquitin Conjugation and Deconjugation in NF-?B Signaling -- Functions of Linear Ubiquitin Chains in the NF-?B Pathway -- Assembly of K11-Linked Ubiquitin Chains by the Anaphase-Promoting Complex -- Ubiquitin Family Members in the Regulation of the Tumor Suppressor p53 -- Ubiquitylation in the ERAD Pathway -- Pupylation -- Sumo Control -- The In Vivo Functions of Desumoylating Enzymes -- Regulatory Functions of Ubiquitin and SUMO in DNA Repair Pathways -- Sumoylation as a Signal for Polyubiquitylation and Proteasomal Degradation -- In Vivo Functions of Isgylation -- Identification and Validation of ISG15 Target Proteins -- FAT10.

520

$a † 1 a a 4 † 17 10 15 ubiquitin; and of 16 VCP 17 18 20 33 34 34 36 p domain. 41 42 42 43 P U 42 47 binding. C. elegans 16 In 21 22 50 51 52 53 13 and UFD 4 10 of Cdc48. 18 30 of Ufd2. COFACTORS 47 23 13 47 47 47 72 15 15 and of Spt23 p90. Ufd2 and Cdc48. In C. elegans 74 16 75 75 76 76 Ufd2 25 54 54 7 56 p47 7 7 80 30 30 81 82 82 but and CD3 26 DUB COFACTORS 30 UFD3 OTU1 4 Cdc48 30 4 OLE1. 15 27 87 REFERENCES 30 REGULATION OF UBIQUITIN MONOUBIQUITINATION UBIQUITINATION 1 32 7 S) d 33 12 13 14 15 18 19 15 20 21 35 15 15 27 15 31 32 31 33 36 monoubiquitination of pol pol 34 37 34 monoubiquitination. 20 35 trans 3 15 REFERENCES by monoubiquitination. Mol Cell; 2009. UBIQUITIN LIGASE ACTIVITY BY Nedd 1 2 of 41 5 6 8 fold. 9 13 14 edd 43 18 18 K M and k 18 22 23 K M 24 25 K M 26 edd 45 18 27 K M K D 18 25 . 8 10 M 21 28 MECHANISM AND REGULATION OF CRLs 34 41 34 edd 47 48 S. pombe 49 51 p27 and I by SCF and SCF 57 58 59 60 CTD CTD CTD CTD in Cul5 CTD CTD CTD 60 18.

650

$a LIFE SCIENCES.

650

$a HUMAN PHYSIOLOGY.

650

$a MOLECULAR BIOLOGY.

650

$a PROTEINS.

650

$a Life Sciences.

650

$a Protein Science.

650

$a Human Physiology.

650

$a Molecular Medicine.

700

$a Groettrup, Marcus. $e editor.

710

$a SpringerLink (Online service)

773

$t Springer eBooks

776

$i Printed edition: $z 9781441966759

830

$a Subcellular Biochemistry, $x 0306-0225 ; $v 54

856

$u http://dx.doi.org/10.1007/978-1-4419-6676-6

912

$a ZDB-2-SBL

950

$a Biomedical and Life Sciences (Springer-11642)

999

$a VIRTUA

No Reviews to Display

Summary	† 1 a a 4 † 17 10 15 ubiquitin; and of 16 VCP 17 18 20 33 34 34 36 p domain. 41 42 42 43 P U 42 47 binding. C. elegans 16 In 21 22 50 51 52 53 13 and UFD 4 10 of Cdc48. 18 30 of Ufd2. COFACTORS 47 23 13 47 47 47 72 15 15 and of Spt23 p90. Ufd2 and Cdc48. In C. elegans 74 16 75 75 76 76 Ufd2 25 54 54 7 56 p47 7 7 80 30 30 81 82 82 but and CD3 26 DUB COFACTORS 30 UFD3 OTU1 4 Cdc48 30 4 OLE1. 15 27 87 REFERENCES 30 REGULATION OF UBIQUITIN MONOUBIQUITINATION UBIQUITINATION 1 32 7 S) d 33 12 13 14 15 18 19 15 20 21 35 15 15 27 15 31 32 31 33 36 monoubiquitination of pol pol 34 37 34 monoubiquitination. 20 35 trans 3 15 REFERENCES by monoubiquitination. Mol Cell; 2009. UBIQUITIN LIGASE ACTIVITY BY Nedd 1 2 of 41 5 6 8 fold. 9 13 14 edd 43 18 18 K M and k 18 22 23 K M 24 25 K M 26 edd 45 18 27 K M K D 18 25 . 8 10 M 21 28 MECHANISM AND REGULATION OF CRLs 34 41 34 edd 47 48 S. pombe 49 51 p27 and I by SCF and SCF 57 58 59 60 CTD CTD CTD CTD in Cul5 CTD CTD CTD 60 18.
Contents	Activation of Ubiquitin and Ubiquitin-Like Proteins -- Control of Ubiquitin Conjugation by Cdc48 and Its Cofactors -- Regulation of Ubiquitin Receptors by Coupled Monoubiquitination -- Control of Cullin-Ring Ubiquitin Ligase Activity by Nedd8 -- Control of Deneddylation by the COP9 Signalosome -- Mechanism, Specificity and Structure of the Deubiquitinases -- Ubiquitin Conjugation and Deconjugation in NF-?B Signaling -- Functions of Linear Ubiquitin Chains in the NF-?B Pathway -- Assembly of K11-Linked Ubiquitin Chains by the Anaphase-Promoting Complex -- Ubiquitin Family Members in the Regulation of the Tumor Suppressor p53 -- Ubiquitylation in the ERAD Pathway -- Pupylation -- Sumo Control -- The In Vivo Functions of Desumoylating Enzymes -- Regulatory Functions of Ubiquitin and SUMO in DNA Repair Pathways -- Sumoylation as a Signal for Polyubiquitylation and Proteasomal Degradation -- In Vivo Functions of Isgylation -- Identification and Validation of ISG15 Target Proteins -- FAT10.
Subject	LIFE SCIENCES. HUMAN PHYSIOLOGY. MOLECULAR BIOLOGY. PROTEINS. Life Sciences. Protein Science. Human Physiology. Molecular Medicine.
Multimedia	http://dx.doi.org/10.1007/978-1-4419-6676-6