Gene Expression and Its Discontents [electronic resource] : The Social Production of Chronic Disease / by Rodrick Wallace, Deborah Wallace.

Return to search

Call Number	611.01816 599.935
Author	Wallace, Rodrick. author.
Title	Gene Expression and Its Discontents The Social Production of Chronic Disease / by Rodrick Wallace, Deborah Wallace.
Physical Description	IX, 227 p. online resource.
Contents	Models of development -- Groupoid symmetries -- Epigenetic catalysis -- Developmental disorders -- An interim perspective -- The obesity pandemic in the US -- Coronary heart disease in the US -- Cancer: a developmental perspective -- Autoimmune disorders -- Demoralization and obesity in Upper Manhattan -- Death at an early age: AIDS and related mortality in New York City -- Final thoughts -- Mathematical appendix -- References.
Summary	A cognitive paradigm for gene expression, via the asymptotic limit theorems of information theory, allows better understanding of how embedding context affects the development of organisms. In sum, epigenetic information sources act as tunable catalysts, directing ontogeny into characteristic pathways, a perspective having important implications for epigenetic epidemiology. The authors show how environmental stressors, in a large sense, can induce a broad spectrum of developmental dysfunctions, and examine a number of pandemic chronic diseases, using U.S. data at different scales on the effects of the legacy of slavery compounded by accelerating industrial and urban decay. Developmental disorders, broadly taken, are unlikely to respond to medical interventions in the face of serious, persistent individual and community stress. In particular, drugs powerful enough to affect deleterious epigenetic programming will likely trigger side effects leading to shortened lifespan. The address of pandemic chronic disease requires significant large-scale changes in public policy and resource allocation.
Added Author	Wallace, Deborah. author. SpringerLink (Online service)
Subject	MEDICINE. HUMAN GENETICS. PUBLIC HEALTH. EPIDEMIOLOGY. BIOINFORMATICS. BIOCHEMISTRY. Biomedicine. Human Genetics. Epidemiology. Biochemistry, general. Computational Biology/Bioinformatics. Public Health.
Multimedia	http://dx.doi.org/10.1007/978-1-4419-1482-8

Libraries with this item

950	Biomedical and Life Sciences (Springer-11642)

Total Ratings: 0

Copies
MARC Record
Reviews
Details


No records found to display.

03336nam a22005655i 4500

001

vtls001568407

003

VRT

005

20170831183200.0

007

cr nn 008mamaa

008

170831s2010 xxu| s |||| 0|eng d

020

$a 9781441914828 $9 978-1-4419-1482-8

024

$a 10.1007/978-1-4419-1482-8 $2 doi

035

$a (DE-He213)978-1-4419-1482-8

039

$a 201708311832 $b santha $y 201708311323 $z vjs2012

050

$a RB155-155.8

050

$a QH431

072

$a MFN $2 bicssc

072

$a MED107000 $2 bisacsh

082

$a 611.01816 $2 23

082

$a 599.935 $2 23

100

$a Wallace, Rodrick. $e author.

245

$a Gene Expression and Its Discontents $h [electronic resource] : $b The Social Production of Chronic Disease / $c by Rodrick Wallace, Deborah Wallace.

264

$a New York, NY : $b Springer New York, $c 2010.

300

$a IX, 227 p. $b online resource.

336

$a text $b txt $2 rdacontent

337

$a computer $b c $2 rdamedia

338

$a online resource $b cr $2 rdacarrier

347

$a text file $b PDF $2 rda

505

$a Models of development -- Groupoid symmetries -- Epigenetic catalysis -- Developmental disorders -- An interim perspective -- The obesity pandemic in the US -- Coronary heart disease in the US -- Cancer: a developmental perspective -- Autoimmune disorders -- Demoralization and obesity in Upper Manhattan -- Death at an early age: AIDS and related mortality in New York City -- Final thoughts -- Mathematical appendix -- References.

520

$a A cognitive paradigm for gene expression, via the asymptotic limit theorems of information theory, allows better understanding of how embedding context affects the development of organisms. In sum, epigenetic information sources act as tunable catalysts, directing ontogeny into characteristic pathways, a perspective having important implications for epigenetic epidemiology. The authors show how environmental stressors, in a large sense, can induce a broad spectrum of developmental dysfunctions, and examine a number of pandemic chronic diseases, using U.S. data at different scales on the effects of the legacy of slavery compounded by accelerating industrial and urban decay. Developmental disorders, broadly taken, are unlikely to respond to medical interventions in the face of serious, persistent individual and community stress. In particular, drugs powerful enough to affect deleterious epigenetic programming will likely trigger side effects leading to shortened lifespan. The address of pandemic chronic disease requires significant large-scale changes in public policy and resource allocation.

650

$a MEDICINE.

650

$a HUMAN GENETICS.

650

$a PUBLIC HEALTH.

650

$a EPIDEMIOLOGY.

650

$a BIOINFORMATICS.

650

$a BIOCHEMISTRY.

650

$a Biomedicine.

650

$a Human Genetics.

650

$a Epidemiology.

650

$a Biochemistry, general.

650

$a Computational Biology/Bioinformatics.

650

$a Public Health.

700

$a Wallace, Deborah. $e author.

710

$a SpringerLink (Online service)

773

$t Springer eBooks

776

$i Printed edition: $z 9781441914811

856

$u http://dx.doi.org/10.1007/978-1-4419-1482-8

912

$a ZDB-2-SBL

950

$a Biomedical and Life Sciences (Springer-11642)

999

$a VIRTUA

No Reviews to Display

Summary	A cognitive paradigm for gene expression, via the asymptotic limit theorems of information theory, allows better understanding of how embedding context affects the development of organisms. In sum, epigenetic information sources act as tunable catalysts, directing ontogeny into characteristic pathways, a perspective having important implications for epigenetic epidemiology. The authors show how environmental stressors, in a large sense, can induce a broad spectrum of developmental dysfunctions, and examine a number of pandemic chronic diseases, using U.S. data at different scales on the effects of the legacy of slavery compounded by accelerating industrial and urban decay. Developmental disorders, broadly taken, are unlikely to respond to medical interventions in the face of serious, persistent individual and community stress. In particular, drugs powerful enough to affect deleterious epigenetic programming will likely trigger side effects leading to shortened lifespan. The address of pandemic chronic disease requires significant large-scale changes in public policy and resource allocation.
Contents	Models of development -- Groupoid symmetries -- Epigenetic catalysis -- Developmental disorders -- An interim perspective -- The obesity pandemic in the US -- Coronary heart disease in the US -- Cancer: a developmental perspective -- Autoimmune disorders -- Demoralization and obesity in Upper Manhattan -- Death at an early age: AIDS and related mortality in New York City -- Final thoughts -- Mathematical appendix -- References.
Subject	MEDICINE. HUMAN GENETICS. PUBLIC HEALTH. EPIDEMIOLOGY. BIOINFORMATICS. BIOCHEMISTRY. Biomedicine. Human Genetics. Epidemiology. Biochemistry, general. Computational Biology/Bioinformatics. Public Health.
Multimedia	http://dx.doi.org/10.1007/978-1-4419-1482-8