Lipids in Health and Disease [electronic resource] / edited by Peter J. Quinn, Xiaoyuan Wang.
| Call Number | 612 |
| Title | Lipids in Health and Disease edited by Peter J. Quinn, Xiaoyuan Wang. |
| Physical Description | XXII, 598 p. online resource. |
| Series | Subcellular Biochemistry, 0306-0225 ; 49 |
| Contents | Fatty Acids -- Transcriptional Regulation of Hepatic Fatty Acid Metabolism -- Modulation of Protein Function by Isoketals and Levuglandins -- Signalling Pathways Controlling Fatty Acid Desaturation -- Fatty Acid Amide Hydrolase: A Gate-Keeper of the Endocannabinoid System -- Modulation of Inflammatory Cytokines by Omega-3 Fatty Acids -- Eicosanoids in Tumor Progression and Metastasis -- Fatty Acid Synthase Activity in Tumor Cells -- Phospholipids -- Lipids in the Assembly of Membrane Proteins and Organization of Protein Supercomplexes: Implications for Lipid-linked Disorders -- Altered Lipid Metabolism in Brain Injury and Disorders -- Lysophospholipid Activation of G Protein-Coupled Receptors -- Phospholipid-Mediated Signaling and Heart Disease -- The Role of Phospholipid Oxidation Products in Inflammatory and Autoimmune Diseases -- Mediation of Apoptosis by Oxidized Phospholipids -- Sphingolipids -- Regulation of lipid metabolism by sphingolipids -- Multiple Roles for Sphingolipids in Steroid Hormone Biosynthesis -- Roles of Bioactive Sphingolipids in Cancer Biology and Therapeutics -- Glycosphingolipid Disorders of the Brain -- Role of Neutral Sphingomyelinases in Aging and Inflammation -- Sphingolipid Metabolizing Enzymes as Novel Therapeutic Targets -- Ceramide-Enriched Membrane Domains in Infectious Biology and Development -- Lipidomics -- MALDI-TOF MS Analysis of Lipids from Cells, Tissues and Body Fluids -- Lipidomics in diagnosis of lipidoses. |
| Summary | Lipids are functionally versatile molecules. They have evolved from relatively simple hydrocarbons that serve as depot storages of metabolites and barriers to the permeation of solutes into complex compounds that perform a variety of signalling functions in higher organisms. This volume is devoted to the polar lipids and their constituents. We have omitted the neutral lipids like fats and oils because their function is generally to act as deposits of metabolizable substrates. The sterols are also outside the scope of the present volume and the reader is referred to volume 28 of this series which is the subject of cholesterol. The polar lipids are comprised of fatty acids attached to either glycerol or sphingosine. The fatty acids themselves constitute an important reservoir of substrates for conversion into families of signalling and modulating molecules including the eicosanoids amongst which are the prostaglandins, thromboxanes and leucotrienes. The way fatty acid metabolism is regulated in the liver and how fatty acids are desaturated are subjects considered in the first part of this volume. This section also deals with the modulation of protein function and inflammation by unsaturated fatty acids and their derivatives. New insights into the role of fatty acid synthesis and eicosenoid function in tumour progression and metastasis are presented. |
| Added Author | Quinn, Peter J. editor. Wang, Xiaoyuan. editor. SpringerLink (Online service) |
| Subject | MEDICINE. HUMAN PHYSIOLOGY. BIOCHEMISTRY. LIPIDS. Biomedicine. Human Physiology. Biomedicine general. Biochemistry, general. Lipidology. |
| Multimedia |
-
Libraries with this item
-
950 BiomedicalandLifeSciences(Springer-11642)
Total Ratings:
0
04536nam a22005295i 4500
001
vtls001568185
003
VRT
005
20170831181900.0
007
cr nn 008mamaa
008
170831s2008 ne | s |||| 0|eng d
020
$a 9781402088315 $9 978-1-4020-8831-5
024
7
$a 10.1007/978-1-4020-8831-5 $2 doi
035
$a (DE-He213)978-1-4020-8831-5
039
9
$a 201708311819 $b santha $y 201708311315 $z vjs2012
050
4
$a QP34-38
072
7
$a MFG $2 bicssc
072
7
$a MED075000 $2 bisacsh
082
0
4
$a 612 $2 23
245
1
0
$a Lipids in Health and Disease $h [electronic resource] / $c edited by Peter J. Quinn, Xiaoyuan Wang.
264
1
$a Dordrecht : $b Springer Netherlands, $c 2008.
300
$a XXII, 598 p. $b online resource.
336
$a text $b txt $2 rdacontent
337
$a computer $b c $2 rdamedia
338
$a online resource $b cr $2 rdacarrier
347
$a text file $b PDF $2 rda
490
1
$a Subcellular Biochemistry, $x 0306-0225 ; $v 49
505
0
$a Fatty Acids -- Transcriptional Regulation of Hepatic Fatty Acid Metabolism -- Modulation of Protein Function by Isoketals and Levuglandins -- Signalling Pathways Controlling Fatty Acid Desaturation -- Fatty Acid Amide Hydrolase: A Gate-Keeper of the Endocannabinoid System -- Modulation of Inflammatory Cytokines by Omega-3 Fatty Acids -- Eicosanoids in Tumor Progression and Metastasis -- Fatty Acid Synthase Activity in Tumor Cells -- Phospholipids -- Lipids in the Assembly of Membrane Proteins and Organization of Protein Supercomplexes: Implications for Lipid-linked Disorders -- Altered Lipid Metabolism in Brain Injury and Disorders -- Lysophospholipid Activation of G Protein-Coupled Receptors -- Phospholipid-Mediated Signaling and Heart Disease -- The Role of Phospholipid Oxidation Products in Inflammatory and Autoimmune Diseases -- Mediation of Apoptosis by Oxidized Phospholipids -- Sphingolipids -- Regulation of lipid metabolism by sphingolipids -- Multiple Roles for Sphingolipids in Steroid Hormone Biosynthesis -- Roles of Bioactive Sphingolipids in Cancer Biology and Therapeutics -- Glycosphingolipid Disorders of the Brain -- Role of Neutral Sphingomyelinases in Aging and Inflammation -- Sphingolipid Metabolizing Enzymes as Novel Therapeutic Targets -- Ceramide-Enriched Membrane Domains in Infectious Biology and Development -- Lipidomics -- MALDI-TOF MS Analysis of Lipids from Cells, Tissues and Body Fluids -- Lipidomics in diagnosis of lipidoses.
520
$a Lipids are functionally versatile molecules. They have evolved from relatively simple hydrocarbons that serve as depot storages of metabolites and barriers to the permeation of solutes into complex compounds that perform a variety of signalling functions in higher organisms. This volume is devoted to the polar lipids and their constituents. We have omitted the neutral lipids like fats and oils because their function is generally to act as deposits of metabolizable substrates. The sterols are also outside the scope of the present volume and the reader is referred to volume 28 of this series which is the subject of cholesterol. The polar lipids are comprised of fatty acids attached to either glycerol or sphingosine. The fatty acids themselves constitute an important reservoir of substrates for conversion into families of signalling and modulating molecules including the eicosanoids amongst which are the prostaglandins, thromboxanes and leucotrienes. The way fatty acid metabolism is regulated in the liver and how fatty acids are desaturated are subjects considered in the first part of this volume. This section also deals with the modulation of protein function and inflammation by unsaturated fatty acids and their derivatives. New insights into the role of fatty acid synthesis and eicosenoid function in tumour progression and metastasis are presented.
650
0
$a MEDICINE.
650
0
$a HUMAN PHYSIOLOGY.
650
0
$a BIOCHEMISTRY.
650
0
$a LIPIDS.
650
1
4
$a Biomedicine.
650
2
4
$a Human Physiology.
650
2
4
$a Biomedicine general.
650
2
4
$a Biochemistry, general.
650
2
4
$a Lipidology.
700
1
$a Quinn, Peter J. $e editor.
700
1
$a Wang, Xiaoyuan. $e editor.
710
2
$a SpringerLink (Online service)
773
0
$t Springer eBooks
776
0
8
$i Printed edition: $z 9781402088308
830
0
$a Subcellular Biochemistry, $x 0306-0225 ; $v 49
856
4
0
$u http://dx.doi.org/10.1007/978-1-4020-8831-5
912
$a ZDB-2-SBL
950
$a Biomedical and Life Sciences (Springer-11642)
999
$a VIRTUA
No Reviews to Display
| Summary | Lipids are functionally versatile molecules. They have evolved from relatively simple hydrocarbons that serve as depot storages of metabolites and barriers to the permeation of solutes into complex compounds that perform a variety of signalling functions in higher organisms. This volume is devoted to the polar lipids and their constituents. We have omitted the neutral lipids like fats and oils because their function is generally to act as deposits of metabolizable substrates. The sterols are also outside the scope of the present volume and the reader is referred to volume 28 of this series which is the subject of cholesterol. The polar lipids are comprised of fatty acids attached to either glycerol or sphingosine. The fatty acids themselves constitute an important reservoir of substrates for conversion into families of signalling and modulating molecules including the eicosanoids amongst which are the prostaglandins, thromboxanes and leucotrienes. The way fatty acid metabolism is regulated in the liver and how fatty acids are desaturated are subjects considered in the first part of this volume. This section also deals with the modulation of protein function and inflammation by unsaturated fatty acids and their derivatives. New insights into the role of fatty acid synthesis and eicosenoid function in tumour progression and metastasis are presented. |
| Contents | Fatty Acids -- Transcriptional Regulation of Hepatic Fatty Acid Metabolism -- Modulation of Protein Function by Isoketals and Levuglandins -- Signalling Pathways Controlling Fatty Acid Desaturation -- Fatty Acid Amide Hydrolase: A Gate-Keeper of the Endocannabinoid System -- Modulation of Inflammatory Cytokines by Omega-3 Fatty Acids -- Eicosanoids in Tumor Progression and Metastasis -- Fatty Acid Synthase Activity in Tumor Cells -- Phospholipids -- Lipids in the Assembly of Membrane Proteins and Organization of Protein Supercomplexes: Implications for Lipid-linked Disorders -- Altered Lipid Metabolism in Brain Injury and Disorders -- Lysophospholipid Activation of G Protein-Coupled Receptors -- Phospholipid-Mediated Signaling and Heart Disease -- The Role of Phospholipid Oxidation Products in Inflammatory and Autoimmune Diseases -- Mediation of Apoptosis by Oxidized Phospholipids -- Sphingolipids -- Regulation of lipid metabolism by sphingolipids -- Multiple Roles for Sphingolipids in Steroid Hormone Biosynthesis -- Roles of Bioactive Sphingolipids in Cancer Biology and Therapeutics -- Glycosphingolipid Disorders of the Brain -- Role of Neutral Sphingomyelinases in Aging and Inflammation -- Sphingolipid Metabolizing Enzymes as Novel Therapeutic Targets -- Ceramide-Enriched Membrane Domains in Infectious Biology and Development -- Lipidomics -- MALDI-TOF MS Analysis of Lipids from Cells, Tissues and Body Fluids -- Lipidomics in diagnosis of lipidoses. |
| Subject | MEDICINE. HUMAN PHYSIOLOGY. BIOCHEMISTRY. LIPIDS. Biomedicine. Human Physiology. Biomedicine general. Biochemistry, general. Lipidology. |
| Multimedia |