1-Benzopyran-4(4H)-ones as novel activated alkenes in the Baylis-Hillman reaction: A simple and facile synthesis of indolizine-fused-chromones

Abstract

1-Benzopyran-4(4H)-one derivatives have been successfully employed as novel activated alkenes in the Baylis-Hillman coupling with heteroaromatic-aldehydes, nitrobenzaldehydes and isatin-derivatives and the corresponding adducts, derived from pyridine-2-carboxaldehyde, have been transformed into a novel indolizine-fused-chromone framework. © 2003 Elsevier Science Ltd. All rights reserved.