Successful Reconstruction of Damaged Ocular Outer Surface in Humans using Limbal and Conjuctival Stem Cell Culture Methods

dc.contributor.author Sangwan, Virender S.
dc.contributor.author Vemuganti, Geeta Kashyap
dc.contributor.author Singh, Shashi
dc.contributor.author Balasubramanian, D.
dc.date.accessioned 2022-03-27T04:10:59Z
dc.date.available 2022-03-27T04:10:59Z
dc.date.issued 2003-08-01
dc.description.abstract When the ocular outer surface is badly damaged, subsequent corneal transplantation fails due to the absence of basal cells that are needed to support the graft. With the realization that the limbus and the conjunctiva have adult stem cells that can be cultured, it has been possible for us to explant culture these on de-epithelized human amniotic membrane, and to graft the resulting viable and transparent epithelium to 125 needy human patients with success. Ultrastructural, histological, biochemical and immunological assays establish the identity of the cells and the tissue formed.
dc.identifier.citation Bioscience Reports. v.23(4)
dc.identifier.issn 01448463
dc.identifier.uri 10.1023/B:BIRE.0000007690.43273.73
dc.identifier.uri https://portlandpress.com/bioscirep/article/23/4/169/54811/Successful-Reconstruction-of-Damaged-Ocular-Outer
dc.identifier.uri https://dspace.uohyd.ac.in/handle/1/6648
dc.subject Adult stem sells
dc.subject Conjunctiva
dc.subject Human amniotic membrane explant culture
dc.subject Limbus
dc.subject Ocular outer surface
dc.subject Sornea
dc.title Successful Reconstruction of Damaged Ocular Outer Surface in Humans using Limbal and Conjuctival Stem Cell Culture Methods
dc.type Journal. Article
dspace.entity.type
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Plain Text
Description: