A chromenoquinoline-based fluorescent off-on thiol probe for bioimaging
A chromenoquinoline-based fluorescent off-on thiol probe for bioimaging
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Date
2012-02-13
Authors
Kand, Dnyaneshwar
Kalle, Arunasree Marasanapalli
Varma, Sreejith Jayasree
Talukdar, Pinaki
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Abstract
A new chromenoquinoline-based fluorescent off-on thiol probe 2 is reported. In aqueous buffer solutions at physiological pH, the probe exhibited 223-fold enhancement in fluorescence intensity by a Michael addition of cysteine to the maleimide appended to a chromenoquinoline. Cell permeability and live cell imaging of thiols are also demonstrated. © 2012 Royal Society of Chemistry.
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Chemical Communications. v.48(21)